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Checklist for long-term safety and metabolic health: Watch for gastrointestinal side effects, especially during dose changes

435,436 Neuronal injury promotes a neuroinflammatory response, leading to the accumulation of immune cells and the release of inflammatory cytokines, contributing to neuronal hypersensitivity

Additionally, G6PD deficiency was assessed by the methemoglobin reduction test, which has a low positive predictive value and therefore may classify individuals as being G6PD-d when they are not 15

n = 5 mice per group

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